For those who are attending the Ancestral Health Symposium this year, my talk will be at 9:00 AM on Saturday. The title is "Insulin and Obesity: Reconciling Conflicting Evidence", and it will focus on the following two questions:
- Does elevated insulin cause obesity; does obesity cause elevated insulin; or both?
- Is there a unifying hypothesis that's able to explain all of the seemingly conflicting evidence cited by each side of the debate?
I'll approach the matter in true scientific fashion: stating hypotheses, making rational predictions based on those hypotheses, and seeing how well the evidence matches the predictions. I'll explore the evidence in a way that has never been done before (to my knowledge), even on this blog.
Why am I giving this talk? Two reasons. First, it's an important question that has implications for the prevention and treatment of obesity, and it has received a lot of interest in the ancestral health community and to some extent among obesity researchers. Second, I study the mechanisms of obesity professionally, I'm wrapping up a postdoc in a lab that has focused on the role of insulin in body fatness (lab of Dr. Michael W. Schwartz), and I've thought about this question a lot over the years-- so I'm in a good position to speak about it.
The talk will be accessible and informative to almost all knowledge levels, including researchers, physicians, and anyone who knows a little bit about insulin. I'll cover most of the basics as we go. I guarantee you'll learn something, whatever your knowledge level.
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