Hyperinsulinemia: Cause or Effect of Obesity?

Is Elevated Insulin the Cause or Effect of Obesity?The carbohydrate hypothesis, in its most popular current incarnation, states that elevated insulin acts on fat cells to cause fat storage, leading to obesity.  This is due to its ability to increase the activity of lipoprotein lipase and decrease the activity of hormone-sensitive lipase, thus creating a net flux of fat into fat cells.  I'm still not sure why this would be the case, considering...

My view on "safe" research

What's that old proverb that everyone used to forward around in the 90s? Work like you don't need the money; dance like no one is watching; sing like no one is listening; love like you've never been hurt; and live life every day as if it were your last.I basically view my research program this way now. I met with a senior colleague recently who started to dispense the "play it safe until you're tenured" advice, then stopped themselves midstream...

i'm feeling a little under the weather today.....hope to be back tomorrow w/ more pep in my step.*image courtesy of splenid willow avenue/ little m...