Ada Lovelace Day 2011

I just realized I nearly missed Ada Lovelace Day (ALD) which is today. (I'm bad with dates, so thanks to Beki for reminding me.)

The person I'd like to honor for ALD is my best friend, who I'll call Sarah. Sarah is actually the person who got me into computers when we were kids. She was always tinkering with electronics in her basement, taking her computer apart, and writing programs. She took all the advanced level science and math classes our school offered, and got top grades. And she was also "cool" - into underground bands, fashion, etc. I tried my best to copy her, though I must admit I got a C in Physics and still don't know how the hell eyelash curlers work.

Sarah was my first female technical role model, and I'm happy to say we're still close friends, and both still working in technology. If this blog wasn't pseudo-anonymous I would brag about what she's currently doing. Suffice to say it is *fabulous*!

The Case for the Food Reward Hypothesis of Obesity, Part II

In this post, I'll explore whether or not the scientific evidence is consistent with the predictions of the food reward hypothesis, as outlined in the last post.

Before diving in, I'd like to address the critique that the food reward concept is a tautology or relies on circular reasoning (or is not testable/falsifiable).  This critique has no logical basis.  The reward and palatability value of a food is not defined by its effect on energy intake or body fatness.  In the research setting, food reward is measured by the ability of food or food-related stimuli to reinforce or motivate behavior (e.g., 1).  In humans, palatability is measured by having a person taste a food and rate its pleasantness in a standardized, quantifiable manner, or sometimes by looking at brain activity by fMRI or related techniques (2).  In rodents, it is measured by observing stereotyped facial responses to palatable and unpalatable foods, which are similar to those seen in human infants.  It is not a tautology or circular reasoning to say that the reinforcing value or pleasantness of food influences food intake and body fatness. These are quantifiable concepts and as I will explain, their relationship with food intake and body fatness can be, and already has been, tested in a controlled manner. 

1.   Increasing the reward/palatability value of the diet should cause fat gain in animals and humans

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