The other day, Stephan Guyenet shared some of his own thoughts on David Despain's can't-say-enough-nice-things-about-it interview with Dr. John Sievenpiper. In case you missed it, Stephan discusses his post looking at the links or lack thereof between sugar consumption per se and obesity. See: Is Sugar Fattening? At the end of the current post is the following footnote:
** If fructose is fattening due to its ability to become fat, then dietary fat should be even more fattening because it doesn't have to undergo an inefficient conversion process-- it's already fat.
Excellent point! I might add that if saturated fat is such a healthy fat for your body, fat produced by de novo lipogenesis -- mostly palmitic acid in the liver -- would be an even better source of that fat as it would give you a "metabolic advantage"! It takes almost no calories to digest and store dietary fat in body fat. It is highly energy intensive to convert fructose to fat, so you get some free calories!
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