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Sabtu, 30 Juni 2012
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The Great Calorie Debate -- A YOUNG biophysicist weighs in
Hat tip to Colby Vorland (@nutsci) via Twitter: New fuel for the calorie debateThis is the blog of one Carson Chow -- half of the dynamic duo who set one Mr. Gary Taubes straight for once and for all about glycerol-3-phosphate -- and routinely puts the man to shame. Oh ... but let it never escape your mind that Chow is *young* ... I hear he's even more *young* than I am *female*!!In any case, Chow picked up on something that I missed...
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More on the Ebbeling et.al. JAMA Study
This started out as a comment on my last post, but got a bit lengthy so I decided to make it a full post. I also addressed some issues with this study in another post those only interested in this study might have missed based on the non-descript title. Let me start by saying that I did a fair amount of updating on my last post after reading the supplemental materials, and as a result I have some new criticisms of this article, and most...
Jumat, 29 Juni 2012
A Friday JAMA-lama Ding Dong!
Well ... I wasn't really going to weigh in further past using that recent JAMA article (EDIT: full text no longer free at JAMA, see link below) as an example of where statistics can lead us astray. But ... as is probably expected, this study has kicked up some dust in the community. I'm sure I'll miss a few, but here's the weighing in so far:Stephan GuyenetAnthony Colpo Marion NestleDon MateszFat HeadThat's just the blog...
Fat Tissue Regulation ~ Part IX: ASP, LPL and the Triglyceride/Fatty Acid Cycle
In this installment, we reunite with our old friend C3KO mouse to learn a little bit more about the role of acylation stimulating protein, ASP, in the regulation of fat tissue (and muscle) from this study: Differential regulation of fatty acid trapping in mouse adipose tissue and muscle by ASP. The C3KO mouse was discussed in Part II of this series. This mouse lacks the gene to produce...
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Kamis, 28 Juni 2012
New Study: Is a Calorie a Calorie?
A new study in JAMA led by Dr. Cara B. Ebbeling and colleagues purports to challenge the idea that all calories are equally fattening (1). Let's have a look. When thinking about the role of calorie intake in body fatness, there are basically three camps:1. Calories don’t matter at all, only diet composition matters.2. Calories are the only thing that matters, and diet composition is irrelevant.3. ...
A Modest Proposal for Peer Review Research
With the advent of, and inexpensive nature of online sharing of information, I propose that all peer-review research should include (anonymous) raw data for each subject. At the very least, there should be scatter plots presented for the individual data points for the main outcomes.I frequently teach statistics, and one of the first things we discuss in that class is sort of the "first purpose" of it all. Because before we can analyze...
Health Care (Insurance) Reform Upheld, but Concentration and Abuse of Power Remain Largely Unaddressed
This may seem like sour grapes, but... Numerous media reports say that the US Supreme Court has upheld the massive US health care "reform" law (look here for Reuters coverage today, and here, for the Los Angeles Times, for example). In my humble opinion, the law will likely increase acess to commercial health care insurance, although will likely not reduce the expense of such insurance, or address the misbehavior of many large...
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