Here's an Experiment I'd Like to See

Ahh, well Jimmy Moore has posted his 90 day update on his nutritional ketosis experiment.  While he's refusing to divulge his menus until the 180 day experiment is complete (wanna bet he writes a book about the experience and stupid people will buy it?) he did finally post a typical meal complete with "recipe" and pictures. Why anyone is even interested in mimicking his foods is beyond me, but that's besides the point.

Here's a "meal", I've added Charles' calorie estimates from nutritiondata.com

direct image link

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Fat Tissue Regulation ~ Part IX: ASP, LPL and the Triglyceride/Fatty Acid Cycle

In this installment, we reunite with our old friend C3KO mouse to learn a little bit more about the role of acylation stimulating protein, ASP, in the regulation of fat tissue (and muscle) from this study:  Differential regulation of fatty acid trapping in mouse adipose tissue and muscle by ASP.  The C3KO mouse was discussed in Part II of this series.  This mouse lacks the gene to produce a protein called C3 (short for Complement 3) which is a precursor for the formation of ASP.  Thus C3KO mice are ASP deficient.  The C3KO is to ASP as a type1 diabetic is to insulin.  These mice are also resistant to obesity.  BTW, hyperASPemia accompanies the hyperinsulinemia and hyperleptinemia of obesity when it's measured.

ASP-deficient mice have delayed postprandial triglyceride (TG) clearance and reduced WAT mass. The objective of this study was to examine the mechanism(s) by which ASP deficiency induces differences in postprandial TG clearance and body composition in male KO mice.

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Physician Phollies ~ II: Dr. William "Wheat Belly" Davis

Next up in our "how can he/she even say that?" series of blatantly erroneous things said by practicing physicians in furtherance of the carbophobic agenda ...

I bring you, an Asylum favorite, Dr. William "Wheat Belly" Davis.  In the most recent post on his WB blog, Wheat Belly trips over himself trying to implicate wheat, specifically, in the diabetes epidemic.  

But can we blame diabetes on wheat?
Yes, absolutely, as much as you can blame poor oral hygience for toothlessness in West Virginia.

Wow!  Gratuitous slam on WVa's aside, Dr. Wee Bee goes on  to list all the ways wheat causes diabetes:

–Any food that increases blood sugar to high levels (i.e., high glycemic index) also increases insulin to high levels. Repetitive high insulin leads to insulin resistance, which leads to visceral fat deposition, more insulin resistance, inflammation, etc., eventuating in diabetes.
–High blood sugar, such as that resulting from eating two slices of whole wheat bread, is toxic to pancreatic beta cells, the cells that produce insulin: glucotoxicity.
–Triglyceride-containing lipoproteins, such as chylomicrons and its remnants, are toxic to pancreatic beta cells: lipotoxicity.

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