Warung Bebas

Minggu, 01 Juli 2012

Revisiting the "Cafeteria Rat" Study -- Why Doesn't Everyone Get Fat?

I was thinking these past few days a lot about scatter plots ... yeah, I'm a geek.  But in that recent n=21 Ebbeling et.al. study, as chaotic as the plots (and connecting lines in that case)  were, they are still instructive.  And apparently some think I should be on a mission to cure obesity by finding out why their wives can eat crap and not get fat, I was reminded of the scatter plots in "Cafeteria Rat" study:  Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet.  


To summarize that study, they took four groups (n's varied for various legs of this study) of a normal strain of rats (Wistar, not genetically predisposed towards obesity) and fed them ad libitum on one of four diets, for 10-15 weeks.
1.  SC control (estimated <5% simple sugars, 12% fat)2.  HF chow - 45% fat, lard3.  LF - low fat (10% lard & soybean oil) matched to HF chow with sucrose substituted for fat content4.  CAF = SC + 3 human snack foods varied daily from a list
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