Statistical analyses do not address these two things.   I'm not sure which podcast it was, there have been a few, with the dynamic Chris duo (Kresser with Masterjohn), but Chris made the comment {paraphrase big time} that the best way to change your LDL particle size favorably was to have a different test done.  I'd love a link gang, if this rings a bell for you.   LDL is not even measured directly in some (most?  all?) analyses of blood lipids.  So first, Chris addressed the error in the measurement.    And I think they discussed the normal day-to-day variability in the lipoprotein concentrations in that same installment as well.  Now I don't want to put numbers/words in Chris' mouth but I've heard similar statements from countless others -- the number 20 point fluctuations in LDL comes to mind.  
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