Quality Low Carb Science?

A while back I asked if anyone had any evidence that insulin blocks leptin action in the brain.  There were many responses both here and on Twitter -- thanks!! -- one of which referenced the following study:  Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults, PA Velasquez-Mieyer, PA Cowan, KL Arheart, CK Buffington, KA Spencer, BE Connelly, GW Cowan, and RH Lustig.  If you're the person pointed me to this, I apologize for not naming you.  Ahhhh Robert Lustig.  Haven't spent much time on him here, but as he muscles his way into the (misguided) War on Insulin, this too shall change.  

I will have much more to say about that study on the whole at some future date.  They gave some people an insulin-lowering drug (a drug that does more than just suppress secretion) and some lost "significant" weight, some lost a wee bit, and some even gained weight.  In reading the intro, I'm becoming increasingly dejected over the quality of peer review these days ... but that too will be part of the subsequent analysis of this study as a whole.

Read more »

Excess protein turned to glucose?

It seems that part of the more recent trend of defining a "proper" low carb diet as being one that is moderate in protein and high (very) in fat is this notion that excess protein will just be turned to glucose.  Quite often I've seen Dr. Richard Bernstein cautions against eating too much protein because it just gets turned to glucose.  (I did look for a link but was unsuccessful, so if I'm misstating Bernstein here, please do correct me in comments.)   I had looked into this long ago, but never really said much about it, but there are two reasons why this never made sense to me.

First, a little biochemistry.  There are exceedingly few reactions that occur in our bodies without the involvement of an enzyme.   This includes not only anabolic (synthesis, building, energy storing/requiring) reactions, but also catabolic (break down, energy releasing reactions) reactions.  Glucose and fatty acids no more "spontaneously combust" in our bodies than does propane in my grill.  Enzymes are the catalysts of reactions, and reactions that require energy (all of those "genesis" reactions for example) are coupled with energy producing reactions that "drive" them.   Enzyme action is regulated by the amount of the enzyme produced and/or some mechanism of activating/deactivating the enzyme.  While enzyme mediated reactions can be related to substrate (reactant) availability and/or influenced by product availability/build-up, this isn't always the case.  I'd even go so far as to say that unless the reaction occurs in a highly compartmentalized fashion (e.g. within mitochondria), substrate/product concentrations generally have little effect on the reaction rates directly. 

Read more »

Does anyone in the audience own ...

... Heller & Heller's Carbohydrate Addicts Diet?  I'm interested in finding out what the 17 questions to determine if you're a carb addict are.  Any help appreciated.  I presume it includes some of these 10 questions?
http://www.carbohydrateaddicts.com/caquiz.html

Thanks in advance!

Belajar Blogging : Cara Membuat Iklan Melayang Dengan Tombol Close

Berikut Cara Membuat Iklan Melayang Dengan Tombol Close :

1. Login Ke Blogger.com dengan ID anda.
2. Masuk ke Tab Tata Letak.
3. Pilih Elemen Halaman.
4. Klik Tambah Gadget.
5. Pilih HTML Javascrib.
6. Copy kode di bawah ini :
   
   
   

   <a onblur="try {parent.
   deselectBloggerImageGracefully();} catch(e) {}" href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiLc-Z_ktU2l7RBAYrwLFBLni2YyawHSG-iwwxsDhxw6IY2KvYt3aaD3IuX4L42QdupG9hgIrv-e88HUQHVBwUeqYxxADAjlum1wqbgjmqN8bHI1TBOPXt6c04azKvNNOG6P2BPX6fd7LY/s1600-h/Widget.JPG"><img style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 400px; height: 300px;" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiLc-Z_ktU2l7RBAYrwLFBLni2YyawHSG-iwwxsDhxw6IY2KvYt3aaD3IuX4L42QdupG9hgIrv-e88HUQHVBwUeqYxxADAjlum1wqbgjmqN8bHI1TBOPXt6c04azKvNNOG6P2BPX6fd7LY/s400/Widget.JPG" alt="" id="BLOGGER_PHOTO_ID_5433478876639914642" border="0" /></a>

   
   

   <style type="text/css">
   #gb{
   position:fixed;
   top:10px;
   z-index:+1000;
   }
   * html #gb{position:relative;}
   
   .gbcontent{
   float:right;
   border:2px solid #A5BD51;
   background:#ffffff;
   padding:10px;
   }
   </style>
   
   <script type="text/javascript">
   function showHideGB(){
   var gb = document.getElementById("gb");
   var w = gb.offsetWidth;
   gb.opened ? moveGB(0, 30-w) : moveGB(20-w, 0);
   gb.opened = !gb.opened;
   }
   function moveGB(x0, xf){
   var gb = document.getElementById("gb");
   var dx = Math.abs(x0-xf) > 10 ? 5 : 1;
   var dir = xf>x0 ? 1 : -1;
   var x = x0 + dx * dir;
   gb.style.top = x.toString() + "px";
   if(x0!=xf){setTimeout("moveGB("+x+", "+xf+")", 10);}
   }
   </script>
   
   <div id="gb">
   
   <div class="gbtab" onclick="showHideGB()"> </div>
   
   <div class="gbcontent">
   
   <div style="text-align:right">
   <a href="javascript:showHideGB()">
   .:[Close][Klik 2x]:.
   </a>
   </div>
   <center>

   
   

   Masukkan Kode iklan anda di sini

   
   

   </center>
   
   <script type="text/javascript">
   
   var gb = document.getElementById("gb");
   
   gb.style.center = (30-gb.offsetWidth).toString() + "px";
   
   </script></center></div></div>
7. Klik Simpan dan selesei.
   

Selamat Mencoba...

sumber : http://kolombloggratis.blogspot.com

Tips Cara Mengunci Folder Dengan Folder Extensions

Di masa - masa sekarang.. Semua orang membutuhkan Privacy untuk melindungi identitas / informasi miliknya.. Banyak User yang menyimpan file-filenya di Computer, namun (akan) dengan sangat mudah di duplikasi tanpa bantuan software sekalipun.. Masih mending kalau data tersebut tidak begitu penting.. Namun bagaimana dengan data/dokumen kantor? Misalkan data kantor.. Bukankah, bila data tersebut diduplikat oleh sentuhan jari di mouse computer oleh ”orang yang tak berhak”, malah akan menjadi bahaya? Karena itu, kita semua membutuhkan privacy.. Salah satunya Dengan mengunci ( lock ) folder yang terdapat di Computer kita, Sebetulnya Banyak Aplikasi ( software ) yang dapat digunakan untuk mengunci folder di dalam Computer kita, Bahkan dapat disertai password.. Sebut saja Folder Guard atau juga Folder Icon dari Pear Software. Banyak sebetulnya tapi disini akan saya jelaskan bahwa tak selamanya mengunci ( lock ) folder harus dengan menggunakan software tetapi Bisa juga dengan Folder Extensions, Memang akan ada beberapa kekurangan Namun dengan kemudahannya, kekurangan ini semestinya tertutupi. 

Pertama yang sobat harus lakukan dengan menggunakan Folder Extension yang sudah Windows Integrated, dengan kata lain, bisa digunakan di semua platform Windows ( tested on Windows XP ) Caranya teramat sangat mudah.. Cukup dengan merename sebuah folder dengan ditambahi extension tersebut.. Maka, folder tersebut akan otomatis terkunci.. ( dalam istilah ini, folder tersebut akan berubah fungsi ), 

Langkah-Langkahnya, Pastikan tak ada file terbuka dari dalam folder yang ingin di lock.. Oke.. Misalkan.. Nama ( path ) folder yang ingin di-lock tersebut adalah.. C:\Lock Test Sekarang, Rename Folder tadi dengan Extension berikut :

1. My Computer -  .{20D04FE0-3AEA-1069-A2D8-08002B30309D}
2. Control Panel -  .{21EC2020-3AEA-1069-A2DD-08002B30309D}
3. My Network Places - .{208D2C60-3AEA-1069-A2D7-08002B30309D}
4. HTML Document - .{25336920-03F9-11CF-8FD0-00AA00686F13}
5. Recycle Bin (sering digunakan oleh malware (virus, worm, etc) - .{645FF040-5081-101B-9F08-00AA002F954E}
6. Printers -  .{2227A280-3AEA-1069-A2DE-08002B30309D}

INGAT!!! 

 Setiap Extensi disini dimulai dengan Titik “.”, Open Bracket “{” dan ditutup dengan Close Bracket “}”..Copy Paste dengan Lengkap dan benar, Info : Cara ini Sangat berguna bagi para sobat yang memiliki File - File Rahasia yang tidak untuk diperlihatkan, maupun di copykan ke orang lain.. he..he..he....

Caranya sobat tinggal merename Folder tadi dengan menambahkan salah satu Extension dari pilihan di atas.. Untuk contoh ini, saya akan menggunakan Extension dari My Computer.. ( Ini yang paling bagus, menurut saya.. ) C:\Lock Test akan menjadi C:\Lock Test.{20D04FE0-3AEA-1069-A2D8-08002B30309D} Enter! Dan lihat apa yang terjadi.. Coba Double-Click (Open) Folder tadi.. Pasti anda akan otomatis “Nyasar” ke My Computer.. Silahkan berexperimen dengan extension - extension di atas.. Pilih saja mana yang paling bagus menurut sobat. dan Untuk membuka folder tadi kembali sobat cukup hapus extension nya, Enter.. Maka, Folder sudah bisa diakses seperti semula.. – Additionals –. Karena, mungkin masih beberapa orang mengalami kendala dalam Unlocking Folder yang telah berhasil di lock.. 

Berikut adalah langkah - langkah mengunlocknya :

1. Pastikan Di Explorer - Folder Options ( View ), checkbox bernilai seperti pada nomer 2, 3 dan 4.
2. Show Hidden Files And Folders = ON 
3. Hide Extensions For Known File Types = OFF 
4. Hide Protected Operating System Files ( recommended ) = OFF
5. Refresh Explorer, bila tadinya Extensi blum terlihat. Jika sudah muncul, hapus extensi mulai dari titik “.”, sampai Close Bracket “}”
6. Untuk hasil yang maksimal, Invert Setting Folder Options di atas menjadi seperti nomer 7, 8 dan 9.
7. Hide Hidden Files And Folders = ON 
8. Hide Extensions For Known File Types = ON 
9. Hide Protected Operating System Files ( recommended ) = ON 
10. Refresh Explorer, pasti Extensi sudah tidak terlihat, hehe.. Dengan begini, mempersulit user, bahkan advanced user untuk mengerti dan mempelajari cara kerja Sistem Lock ini.

sumber : http://kolombloggratis.blogspot.com